肥胖抵抗大鼠与肥胖大鼠都有肝脏脂肪变性与胰腺组织受损；

There were fatty degeneration and pancreatic tissue damage in both DIO-R rats and DIO rats.

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作者认为NAFLD是超声扫描下肝脏脂肪变性最常见的致病因素（81.5%）。

The authors note that NAFLD was the most common cause (81.5%) of hepatic steatosis on ultrasound.

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肝脏胰岛素抵抗还表现为脂代谢异常，如甘油三酯释放增加和肝脏脂肪变性，这与FOXO1转录活性增加有密切关系。

Increased triglyceride release and hepatic steatosis are the common features of hepatic insulin resistance, which deeply associated with increased FOXO1 transcription.

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