目的构建以乳铁蛋白作为靶向功能基、可生物降解聚合物泡囊为载体的脑靶向递药系统,并对其脑部递药特性作出药效学评价。
OBJECTIVE to prepare a novel brain targeting system, lactoferrin conjugated self-assembled polymer vesicles (Lf-PVs), which the brain delivery property had been evaluated in vivo.
聚合物胶束与泡囊均系由两亲性分子在水中自组装形成的药物载体。
Polymersome micelles and niosomes are the medication vehicle composed by amphiphilic block copolymer self-assembling in water.
概括了囊泡在反应微环境、药物释放、基因载体和生物矿化等方面的潜在应用;并提出了聚合物构筑囊泡的发展前景。
The potential applications of the polymeric vesicles in some fields, such as micro-circumstance, the release of drug, gene engineering and biomineralization were introduced.
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