本文主要综述了目前红霉素结构改造的研究进展，为解决耐药性问题提供良好途径。
This article summarized the structure reform of Erythromycin to offer the pretty pathway to solve the tolerance.
目的寻找具有良好药代动力学性质和抗耐药性的新一代红霉素衍生物。
Aim to discover new erythromycin a derivatives with good pharmacokinetic profiles and anti-tolerance.
耐替米考星的S6和BG44T菌株对红霉素、泰乐菌素、林可霉素有交叉耐药性。
Tilmicosin-resistant S6 and BG44T showed cross-resistance to erythromycin, tylosin and lincomycin.
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