缺氧诱导因子- 1是近几年研究较多的转录因子，它可使肿瘤在生长侵袭过程中适应缺氧应激，也为肿瘤治疗提供了新思路。
Hypoxia-induced factor-1 is a transcription factor which is widely studied in recent years. It helps progressing tumors adapt to hypoxia stress and also provides a new clue for tumor therapy.
低氧诱导因子1 (HIF - 1)是重要的氧依赖性核转录因子，低氧条件下能上调多个靶基因表达以减少缺氧性损伤。
Hypoxia inducible factor-1 (HIF-1) is a key oxygen-dependent transcription factor that up-regulates many protective genes against hypoxia-induced injury.
缺氧诱导因子1（HIF-1）是近年发现的调控细胞低氧适应性变化的重要转录因子。
Hypoxia-inducible factor-1(HIF-1), a newly discovered factor in recent years, is an important transcription factor which can control the cells′adaptive responses to hypoxia.
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