布雷非德菌素是一种高效的细胞生长抑制剂。1958年第一次被报导，之后又被几个研究小组在一系列不同的生物化验中作为高效活性试剂。
Brefeldin a is a potent inhibitor of cell growth first described in 1958, then independently "rediscovered" by several groups as a potent active in a broad range of bioassays.
目的探讨选择性及非选择性环氧合酶-2抑制剂（COX-2）对体外培养的结肠癌细胞生长的影响及其作用的信号传导通路。
Objective To evaluate the inhibiting effect of selective and non-selective cyclo-oxygenase-2(COX-2) inhibitor on growth of colon cancer cell lines in vitro and its signal transduction pathway.
该研究小组总结认为，这些肿瘤细胞内特殊的EGFR突变确定了抑制剂分子可能可以减慢或者停止那些细胞的生长。
The research team concluded that the particular EGFR mutation within tumor cells determines which inhibitor molecules are likely to be able to slow or stop the growth of those cells.
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