结论:朊蛋白106 - 126肽段能够诱导分化后的PC 12细胞凋亡,具有明确的毒性作用。
Conclusion Prion protein 106-126 peptide can induce apoptosis in differentiated PC12 cells and present cellular toxicity definitely.
结论:朊蛋白106 - 126肽段对分化PC 12细胞具有毒性作用,能量代谢障碍可能是其毒性作用机制之一。
Conclusion: Prion protein 106-126 peptide has cellular toxicity effect on differentiated PC12 cells, and the energy metabolize disorder may be one of the reasons for the toxic mechanism.
这提示朊蛋白可能参与细胞程序化死亡的调控过程。
It suggests that human prion protein might play a role in controlling cell programmed death.
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