. Glomerular extracellular matrix (ECM) accumulation and base-membrane thickness and glomerular mesangial cell proliferation is decreased after treatment of TZDs.
经TZD治疗后糖尿病肾小球内细胞外基质蓄积、基底膜增厚及肾小球系膜细胞增生减轻 。
参考来源 - TZD对糖尿病大鼠肾脏保护作用及机制的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
其保护机制与改善氧化应激、抗炎及抑制系膜细胞增生有关。
In addition, it might relate to inhibitory effect on the proliferation of murine mesangial cells.
结果：肾小球系膜区FN与系膜细胞增生、肾小球损伤程度及肾小管间质损伤程度均呈正相关。
Results Positive correlations were found between the degree of FN in glomerular mesangium or basement membranes and glomerular lesion grading or tubulointerstitial lesion grading.
目的研究反义单核细胞趋化蛋白1 (MCP - 1)对系膜细胞MCP - 1分泌及增生的影响。
Objective To examine the influence of antisense MCP-1 on MCP-1 production and mesangial cell proliferation.
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