人类造成的突变(以地质时期为尺度衡量)，其证据触目惊心。
Evidence of abrupt change — on a geological time scale — wrought by human hands would seem to be overwhelming.
目的定量分析拉米夫定治疗不同时期耐药突变的变化规律，为及时调整治疗方案提供依据。
Objetive to analysis the regulation of lamivudine-resistant mutations quantitatively in the different therapeutic periods, and to provide the evidences for therapeutic regimen adjustment.
纯合子突变小鼠在各个胚胎时期都有预期中的出现比例，在大小与型态上并没有明显的缺陷。
Homozygous mutant mice showed expected ratio and no obvious defect in sizes and morphologies at all embryonic stages examined.
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