结果：热痛觉过敏在肿瘤细胞植入后的12 - 18天发生进展。

RESULTS: Thermal hyperalgesia developed between Days 12 and 18 after cancer cell inoculation.

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背景：慢性痛包括痛觉过敏和痛觉感觉异常，是患者感到难以忍受和临床缺乏治疗手段的一种病理现象。

BACKGROUND: Chronic pain, including hyperalgesia and algesthesia paresthesia, is pathological phenomenons making the patients felt unendurable and lacking of clinical treatments.

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因此，许多研究人员在寻求新的止痛药方时，都会把解除痛觉过敏及异位疼痛列入优先考量。

Many researchers, therefore, have amelioration of hyperalgesia and allodynia foremost in their minds as they hunt for new analgesics.

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