目的:临床试验中对组蛋白脱乙酰基酶阻滞剂(HDACi)的研究目的在于诱导细胞分化,生长停止,和肿瘤细胞的凋亡。
Purpose: Histone deacetylase inhibitors (HDACi) are being studied in clinical trials with the aim to induce cellular differentiation, growth arrest, and apoptosis of tumor cells.
在这方面我正在研究的一种思路就是,如果一个患者只有7三体,我们可以用表皮生长因子受体阻滞剂治疗6个月,观察是否能根除这种克隆。
One of the ideas that I am working on is that if a patient has trisomy 7 only we can give them an epidermal growth factor receptor inhibitor for six months and see if we can eradicate those clones.
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