目的:建立实验性骨质疏松大鼠牙周炎模型,观察用药后大鼠血生化指标、骨密度的变化和组织病理学改变。
Objective: to observe the effect of alendronate and raloxifene on the lever of biochemical indices, histomorphometry and bone density in the experimental osteoporosis and periodontitis rats models.
目的:通过建立大鼠骨质疏松模型,研究雌激素替代治疗对实验性牙周炎大鼠牙槽骨高度的影响。
Objective: To evaluate the effects of estrogen replacement therapy upon alveolar bone height in rats with experimental periodontitis via establishing osteoporosis rats model.
牙周炎动物模型在牙周病病因学、病理学以及防治方面的研究中起着十分重要的作用。
Animal model plays an important role in the study of etiology, pathology, prevention and cure of periodontal disease.
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