Conclusion Rutin is a kind of poorly-soluble drug. Both the solubility and oil-water partition coefficients are concerned with the pH value,which determination could provide the basis for the further study of rutin osmotic pump tablet.
结论芦丁为难溶性药物,其溶解度和油水分配系数都与pH有一定的关系;芦丁溶解度和油水分配系数的测定可为进一步研究芦丁渗透泵片提供基础。
参考来源 - 芦丁的溶解度及油水分配系数研究ondansetron hydrochloride; cellulose acetate; osmotic pumpingtablet; uniform design; two one-side test; bioavailability; in vivo-in vitrocorrelation
盐酸昂丹司琼;醋酸纤维素;渗透泵片;均匀设计;双单侧检验;生物利用度;体内外相关。
参考来源 - 盐酸昂丹司琼渗透泵型控释片剂的研究·2,447,543篇论文数据，部分数据来源于NoteExpress
扩散与溶蚀机制对渗透泵片释药有影响。
Corrosion mechanism and diffusion mechanism have effect on drug release from osmotic pump tablets.
目的制备酒石酸托特罗定渗透泵片，考察其体外释药特性。
OBJECTIVE to prepare the tolterodine osmotic pump tablet and study its release profiles in vitro.
目的以盐酸哌唑嗪为模型药物研究单层芯渗透泵片简化的制备方法。
OBJECTIVE To develop a simplified preparative method for osmotic pump tablet using prazosin hydrochloride as a model drug.
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