本品系由微生物(Streptoverticillum ladakanus)所产生的嘧啶核苷类似物,亦可用化学方法合成。临床上用于治疗乳腺癌、肠癌、黑色素瘤、急性粒细胞性白血病等有一定疗效。
目的:观察脐血间充质干细胞经5-氮杂胞苷诱导在体外定向分化为心肌样细胞的形态学及分子生物学特征。
AIM: To study morphological and molecular biological feature of differentiation of umbilical cord blood stem cells in vitro after induced by 5-azacytidine into cardiomyocytes.
氮杂胞苷(Azacitidine),用于治疗骨髓增生异常综合征(MDS) 一种罕见的恶性血液肿瘤。
Azacitidine is used to treat patients with myelodysplastic syndromes (usually abbreviated, a bit oddly, to MDS), a group of rare and deadly blood malignancies.
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