2、观察脂多糖(LPS)刺激机体产生的IL-1β等细胞因子对GBL诱导失神发作失神样棘慢波(SWDs)的影响。20只SD大鼠随机分为四组，LPS1组、LPS2组、LPS3组及对照组，每组5只。
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即使不出现明显的临床发作，也可以证明有发作阈值降低，即脑电图出现棘波或多棘慢波放电。
Even without obvious clinical seizures, may also prove lower seizure threshold, which appears EEG spikes or spike and wave discharges.
发作期脑电图17例表现为高波幅慢波夹杂棘波爆发-低电压抑制，10例表现为全脑各导呈广泛性低电压抑制，1例表现为假性正常脑电图改变。
Sometimes low voltage restraint outbreaking with high wave, slow waves and spikes appeared in 17 cases while wide low voltage restraint occurred in 10 cases, but false normal EEG appeared in 1 case.
SBSD可表现为棘或尖波、棘慢复合波与快节律三种类型，以棘慢复合波最为常见、占63%。
Three forms of SBSD were found: spikes or sharp waves, spike and wave discharges (the most commonly seen, taking up 63%) and fast activities.
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