包括H2A,H2B,H3,H4 四种组蛋白
人们很早就注意到,真核细胞中核小体核心组蛋白N-端尾部的乙酰化水平与基因活化密切相关。
It has been known for some time that the acetylation of N-termini of core histones in nucleosome is associated with gene activation.
核小体核心由140个碱基对的DNA围绕一个组蛋白小球组成,每一个组蛋白小球包含两个H_2A、H_2B、H3和H4的四聚体分子。
The core consists of 140 base pair of DNA wrapped around a globular histone bead containing two each of histones H2A, H2B, H3 and H4.
组蛋白 H3 与 H2A,H2B,H4 共同构成了真核生物核小体的八聚体核心。
Histone H3 along with H2A, H2B, and H4 form the eukaryotic nucleosome octamer core.
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