它可分为两类： 1．染色单体断裂(chromatid break, ctb) 指一个染色单体被 打断，且远端部分离开了原来的位置，导致染色单体缺失和染色 单体断片。
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结果表明：DCAP是一种染色体损伤剂，诱发的畸变主要为染色单体断裂和交换；
Results showed that DCAP was clastogen and the aberrations were mainly chromatid breaks and exchanges.
它能引起细胞染色单体断裂，增加sce的频率，其SCE频率的出现与克隆形成能力的抑制呈平行相关。
It could induce formation of cellular chromatid breaks and increase the frequency of SCE. The effect of HCPT on SCE was found to parallel to the inhibition of colony formation.
在结构上，染色体型断裂、染色单体型断裂、双着丝粒、双微小体这些畸变，差异也非常显著（P<0.01）。
Structurally, the aberrations of the chromosome-type break, chromatid break, double minute chromosome were also remarkably different (P<0.01).
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