failure of issue
... Failure is the mother of success 失败是成功之母 failure of issue 无子嗣 failure上传：韩萱 ...
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死时无子嗣 die without issue
子嗣无忧 The Kids Are All Right
·2,447,543篇论文数据，部分数据来源于NoteExpress
他死后无子嗣。
He died without issue.
《牛津词典》
他问我的朋友为何生活如此失败，到现在还是单身且无子嗣。
And he asked my friend, single and childless, why she had failed at life.
youdao
大约33%的无子嗣的单身男性确实想结婚，这其中的24%还想要孩子。
About 33% of single males who do not have children want to be married and of those 33%, about 24% want to have children.
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