对NDM - 1的活性至关重要的高温，拥挤的人群，大规模的抗生素过度使用，不足量使用和误用以及落后的感染控制手段都加剧了该基因的传播。
High temperatures, which are important for NDM-1 mobility, a crowded population, massive antibiotic over-use, under-use and misuse and poor infection control also contribute.
正如所指出的，该区域各国具有一系列所谓的“不正当刺激措施”，鼓励和维持着对抗生素的滥用和过度使用。
As noted, countries in this region have a number of so-called "perverse incentives" that encourage and sustain the misuse and overuse of antibiotics.
她说抗生素一直被视为理所当然的治疗手段并且被过度的使用。
She said antibiotics were being taken for granted and overused.
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