侵袭性真菌感染，尤其是念珠菌血症和系统性念珠菌病，在过去几十年已成为发病率和死亡率的主要原因。

Invasive fungal infections, especially candidemia and systemic candidiasis, have become a major cause of morbidity and mortality in the last few decades.

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近来，由于多种抗真菌药物的问世，IDSA的指南出现了一些显著变化，尤其是针对侵袭性真菌感染的治疗。

Recently, there have been several significant changes in IDSA guidelines especially in the treatment of invasive fungal infection because of developments in several antifungal agents.

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