目的研究联合运用狂犬病毒糖蛋白基因重组腺病毒与同一抗原核酸疫苗对小鼠的免疫效果。
Objective To investigate the immune response of mice primed by DNA particle bombing and boosted by immunization with replication-defective adenoviral recombinant bearing rabies glycoprotein gene.
目的:构建表达小鼠轮状病毒(EDIM)EW株VP7基因的重组腺病毒,以在小鼠模型上研究轮状病毒的免疫保护机制。
Objective:To construct a replication defective recombinant adenovirus expressing murine rotavirus(EDIM)EW strain VP7to recruit it in studies on the protective immunization of rotavirus.
目的:克隆人和小鼠的活化t细胞表达与分泌调节基因(RANTES基因)并分别构建腺病毒表达载体。
Objective: to clone the human and murine origin RANTES genes and construct the adenoviral expression vectors.
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