目的探讨高脂饮食诱导肥胖易感(OP)大鼠和肥胖抵抗(OR)大鼠，激素敏感性脂肪酶(HSL)和脂蛋白脂肪酶(LPL)基因表达的差别。

Objective To explore the gene expression of hormone sensitive lipase (HSL) and lipoprotein lipase (LPL) between obesity-prone (op) and obesity-resistant (or) rats induced by a high-fat diet.

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结果糖尿病大鼠心肌脂蛋白脂酶m RNA是升高的，经BMOV治疗后心肌细胞脂蛋白脂酶m RNA表达可降低，基本恢复到正常对照水平。

Results The levels of LPL mRNA in cardiac myocytes of diabetic group increased, but though BMOV treatment the levels of LPL mRNA decreased to control levels.

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结论：泰脂安对高脂模型大鼠有较好的降脂作用，其降脂作用机制可能与泰脂安升高血清中的脂蛋白脂肪酶含量有关。

CONCLUSION: Taizhi "an capsule can decrease the hyperlipidemia. Its mechanism is related to the regulation of lipid metabolism and improvement of the concentration of LPL (lipoprotein lipase)."

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