验研究 研究目的:应用微电极核团毁损术毁损帕金森病(Parkinson's Disease,PD)大鼠的腹侧苍白球(ventral pallidum,VP),观察其旋转行为的变化,检测术后脑内相关神经递质的改变及相应脑区的形态变化,以探讨"细胞刀"治疗PD...
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方法：通过单细胞细胞外记录吗啡依赖大鼠腹侧苍白球的电信号，观察吗啡对放电的影响。
Methods:The firing of ventral pallidal neurons in the action of morphine and naloxone was recorded and analyzed in the morphine dependent rats with extracellular single-unit recording.
方法··：毁损依赖大鼠腹侧苍白球，利用条件性位置偏爱实验测定术前、术后依赖大鼠对注射吗啡侧的偏爱程度，评价腹侧苍白球在药物强化效应程度中的作用。
Method: Electrical lesions of ventral pallidum were done in 12 morphine dependent rats and the drug seeking behavior was measured by conditioned place preference paradigm.
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