...重复区域的大小, 基因重复可分为单个 基因重复、 部分基因组重复(segmental duplication)和 整个基因组重复(genome duplication)即多倍体化. 单 个基因和部分基因组的重复主要通过不等交换产生, 而基因组重复是有丝分裂或减数分裂过程中发生错 误产生的.
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尤其是全基因组重复,对于基因组的进化具有突出的作用。
Gene duplication especially whole-genome duplication has been found as a pivotal factor in the evolution.
如果把人类基因组视作“生命之书”,他们绘制了大量字母或短语的变异——但忽视了“书”中篇幅更大的整页乃至整章的删节和重复内容。
Looking at the human genome as a "book of life" they have mapped vast Numbers of variations in letters or short words - but missed much larger deletions and duplications of pages or chapters.
如果调控紊乱,则基因组畸变累积,如重复的DNA序列甚至出现整条多余的染色体。
When regulation fails, genome aberrations accumulate, including repeated sequences of DNA or een entire extra chromosomes.
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