等位基因受阻突变筛查 allele refractory mutation screening
目前检测EGFR基因突变的方法主要是直接测序，费时，费用较高，不适合用于临床筛查。
Now the most common method to detect EGFR gene mutations was direct sequencing, expensive and time consuming, which didn't fit clinical screening.
目的：观察单链构象多态性(SSCP)筛查akt2基因突变时凝胶配制的不同对筛查结果的影响。
Objective: To observe the effect of different gel preparation on detecting mutation of AKT2 gene by single-strand conformation polymorphism (SSCP).
结论：制作的基因芯片可准确识别嗜铬细胞瘤相关的基因突变，为筛查嗜铬细胞瘤基因突变提供一种快速的方法。
Conclusions: The gene chip could accurately identify genetic mutations related to pheochromocytoma, which could provide a quick method of screening genetic mutations in pheochromocytoma.
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