目的是合成含2-5个碳的直链烷酸功能基的5-氟尿嘧啶衍生物。
The objective is to synthesize 5-fluorouracil derivatives containing 2-5 carbon alkanoic acid.
嘧啶衍生物的合成与转化、生物活性与代谢研究是有意义的。
Studies on the synthesis and conversions, biological activity and metabolism of pyrimidine derivatives are significant.
采用相转移催化法以四丁基氯化铵为催化剂合成了端基含磺胺嘧啶的聚乳酸，将肿瘤导向基团引入了可生物降解药物载体。
Sulfadiazine-polylactide, a tumor targeting drug carrier, was successfully synthesized by the phase transfer catalysis(PTC)with tetrabutyl ammonium chloride hydroxide as catalyst.
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