...肠、肝、胎盘和血脑屏障等部位大量表达,与全分子转运蛋白如P-gp(P-glycoprotcin)和多药耐药蛋白(multi-drug resistance protein,MRP)相似,可以主动地把具有不同化学结构和作用于细胞内不同靶位点的化疗药物泵出胞外,从而引起肿瘤对多种抗癌...
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和多药耐药相关蛋白 multidrug resistance associated protein ; multidrug resistence protein ; MRP ; multidrug associated protein
和多药耐药性相关蛋白 multidrug resistance-associated protein
依赖于半胱氨酸蛋白酶的激活，美沙酮通过激活线粒体克服了白血病细胞中的阿霉素耐药、多药耐药、和凋亡抑制。
Depending on caspase activation, methadone overcomes doxorubicin resistance, multidrug resistance, and apoptosis resistance in leukemia cells through activation of mitochondria.
采用流式细胞术检测骨髓细胞多药耐药蛋白P170的相对表达率，并分析P170表达阳性率与耐药性和性别间的关系。
The expression of multidrug resistance protein P170 in marrow cells was detected by flow cytometry, and the correlations of the expression of P170 with drug resistance and gender were analysed.
目的：建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
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