分 类: 基本有机原料产品 又名：二乙烯酮;3-羟基丁烯酸-β-内酯;Diketen 英文名称:diketene 英文别名:diketen; Ketenedimer,99%; Ketene Dimer; DK; Acetyl ketene; 4-Methylene-2-oxetanone; But-3-en-3-olide; 4-methylideneoxetan-2-one; but-1-ene-1,3-dione
n. diketene
misc. ketene dimer
二乙烯酮;双乙烯酮;乙酰乙烯酮;乙酰基乙烯酮;双烯酮;Diketene;Acety ketene 双烯酮;乙烯基乙烯酮;双乙烯酮;乙烯乙酸-β丙酯;二乙烯酮;3-羟基丁烯酸-β-内酯;Diket……
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... 双乙烯酮;4-亚甲基-2-氧杂环丁酮;双烯酮;乙烯基乙烯酮;Diketene;4-Mcthylene-2-oxetanone;Ketene dimer;Acetylketene 双乙烯酮;二乙烯酮;3-羟基丁烯酸-β-内酯;Diketen ..
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中文名称：双乙烯酮 英文名称：2-Oxetanone,4-methylene- 中文别名：3-羟基丁烯酸-β-内酯;二乙烯酮 英文别名：3-Butenoicacid, 3-hydroxy-, b-lactone (6CI,7CI); 4-M
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Synthesis 3, 5-dihydroxytoluene by ethyl acetoacetate and diketene as material ( yield 6%), by 3-methyl-4-chlorophenol and KOH as material (yield 30-40%) respectively, It was solved for product separation and purify.
分别以乙酰乙酸乙酯与双乙烯酮为原料(收率6％)、3-甲基-4-氯苯酚与氢氧化钾为原料(收率30-40％)合成了3，5-二羟基甲苯，解决了产品分离纯化问题。
参考来源 - 5The optimum conditions of acylation was as follows:reaction temperature was 80~85℃. The mole ratio of diketene and 2-methoxy- ethanol was 1:1; reaction time was 2.5~3h and the optimum catalyts was triethylamine.
在该路线中,双乙烯酮酯化反应的最佳反应条件为:反应温度为80~85℃;双乙烯酮与乙二醇单甲醚的摩尔比为1:1;反应时间为2.5~3h;催化剂为三乙胺。
参考来源 - 西尼地平的合成与拆分·2,447,543篇论文数据，部分数据来源于NoteExpress
结论双乙烯酮具有明显的肝脏和肺脏毒性。
Conclusion Diketene has obvious toxic effects on liver and lung.
本文介绍了双乙烯酮的生产方法，应用和发展趋势。
The production methods, application and market prospect of diketene are introduced in this paper.
目的探讨双乙烯酮对眼部的损伤机制、表现、急救及预防措施。
Objective Study on the mechanism of ocular burn causing by diketene and its manifestation, emergency treatment and preventive measures.
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