生命科学 关键词：胚胎发育；甲基化修饰；甲基化酶；去甲基化酶；表观遗传 [gap=1211]Key words: embryo development; methylated modification; methylase; demethylase; epigenetics
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...专业毕业论文 CdR处理细胞后DNA甲基化转移酶(DNAmethyltransferases,Dnmts)、DNA去甲基化酶(Methyl-DpG binding domain protein 2,Mbd2)mRNA及其蛋白白勺表达变化。
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组蛋白去甲基化酶 histone demethylase ; HDMS ; Histone demethylases
构建去甲基化酶 methyl-CpG binding domain ; MBD
去甲基化酶抑制剂 DMI inhibitors ; DMIS
以及组蛋白去甲基化酶 Histonedemethylase ; HDMS
目的构建去甲基化酶 methyl-CpG binding domain
组蛋白赖氨酸去甲基化酶有可能成为一个新的抗肿瘤治疗靶标。
Therefore, histone lysine demethylases may serve as a new target for anti-cancer therapy.
目的探讨胃癌组织中甲基化酶、去甲基化酶基因与肿瘤相关癌基因和抑癌基因的关系。
Objective To investigate the relationship of the expression of DNA methyltransferase, demethylase(mbd2) and tumor-associated genes in human gastric cancer.
随着组蛋白赖氨酸去甲基化酶的发现，证实组蛋白赖氨酸甲基化是一个可以逆转的组蛋白表遗传修饰。
The discovery of the histone lysine demethylases has strongly demonstrated that histone lysine methylation is a reversible epigenetic modification.
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