去极化肌松药又称为非竞争性肌松药（noncompetitive muscular relaxants），其分子结构与ach相似，并且在神经肌肉接头处不易被胆碱酯酶分解，因而能产生与ach相似但较持久的去极化作用。
... depolarization 去极化 depolarizing relaxant 去极化肌松药 deslanoside 去乙酰毛花甙丙 ...
基于16个网页-相关网页
Non-depolarizing muscle relaxants, almost all there is a slow-starting, strong role in the release of histamine and hemodynamic changes Defects .
非去极化肌松药，几乎都存在着起效慢、组胺释放作用强和血液动力学改变等缺陷。
参考来源 - 不同年龄和性别患者罗库溴铵药效学的比较Conclusion:The tumor patients with depolarizing neuromuscular blocking drugs during induction of anesthesia had a higher rate of train-of-four (91.67%). The rate of phase II block during recovery of anesthesia was 96.15%. antagonism of residual phase II block was successful .
结论 肿瘤患者使用去极化肌松药在诱导期 TOF 发生衰减的比例相当高(总发生率为 91.67%),恢复期发生Ⅱ项阻滞的比例更高(总发生率96.15%),用新斯的明能有效的拮抗去极化肌松药所致Ⅱ相阻滞的肌松残留。
参考来源 - 肿瘤患者使用去极化肌松药发生Ⅱ相阻滞的临床观察·2,447,543篇论文数据，部分数据来源于NoteExpress
目的探讨七氟醚增强非去极化肌松药肌松作用的机制。
Aim To investigate the mechanism of sevoflurane enhancement of muscle relaxation.
另外，非去极化肌松药还可以改变烟碱样受体的类脂膜，改变其离子通道。
In addition, non depolarizing neuromuscular blocking drugs may alter the lipid membrane around the nicotinic cholinergic receptors, changing the properties of the ion channel.
除了利多卡因以外，几乎所有的局麻药都对非去极化型肌松药产生这样的作用。
In addition to lidocaine, nearly all the local anesthetics have been shown to have this effect on neuromuscular blockade.
应用推荐