《国际糖尿病》： 您能向我们介绍一下钠葡萄糖协同转运蛋白2的作用机制吗？

International Diabetes: Can you introduce us to the mechanisms of sodium-glucose cotransporter-2?

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安全助疗效，钠葡萄糖协同转运蛋白2抑制剂，如添加胰岛素在1型糖尿病患者。

Efficacy and Safety of Canagliflozin, a Sodium Glucose Cotransporter 2 Inhibitor, as Add-On to Insulin in Patients With Type 1 Diabetes.

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背景：钠-葡萄糖协同转运蛋白2（SGLT2）在近端肾小管表达，负责重吸收肾小管液中90%的葡萄糖。

Context: Sodium-glucose cotransporter 2 (SGLT2) expressed in the proximal renal tubules accounts for about 90% of the reabsorption of glucose from tubular fluid.

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