副癌综合征(paraneoplastic syndrome)是指那些与肿瘤有关但并非肿瘤细胞侵袭所直接引起的解剖和功能异常。约51%的恶性肿瘤具有这类综合征的表现，肺癌最多。有些症状往往出现于肿瘤发现之前，切除肿瘤后消失，复发时又重现。
目的探讨以副癌综合征为首发症状的原发性肺癌的临床特征及诊断。
Objective To investigate the clinical characteristics and diagnosis of lung cancer with paraneoplastic syndrome as initial symptom.
本文报告由胆囊癌、肝癌、胃癌和肺癌引起的副肿瘤综合征4例。
We have described 4 patients with neurological paraneoplastic syndromes caused by gallbladder, liver, stomach and lung cancer.
应用推荐