肠易激综合征(irritable bowel syndrome, IBS)的多种发病机制中, 内脏高敏感性(visceral hypersensitivity)即结肠对机械刺激出现内脏痛阈水平下降, 结直肠及躯体出现的痛觉过敏(hyperalgesia)是其最重要的特性[1].
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Tests two: To discuss the effect and Mechanism of JPJDHZF on visceral hypersensitivity rat model of IBS.
实验二:探讨健脾解毒化浊方对内脏高敏感性IBS大鼠模型的疗效和作用机理。
参考来源 - 健脾解毒化浊方治疗肠易激综合征的基础及临床研究·2,447,543篇论文数据，部分数据来源于NoteExpress
结论马来酸曲美布汀能改善幼鼠ibs肠黏膜上皮细胞功能，抑制其内脏高敏感性。
Conclusion Trimebutine maleate can inhibit the visceral hypersensitivity and improve the function of the intestinal epithelial cells in IBS young rats.
目的：观察替加色罗治疗内脏高敏感性大鼠前后的脊髓诱发电位(SEP)和脑诱发电位(cep)的变化。
Objective: To study the changes of spinal evoked potentials (SEP) and cerebral evoked potentials (CEP) in visceral hypersensitivity rats before and after treated with Tegaserod.
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