诱导供体特异性的移植耐受(donor specific transplant tolerance,DSTT)是近年来移植免疫研究重点,人们试图通过诱导DSTT使移植物和宿主之间免疫反应达到平衡,宿主将移植物当...
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目的探索建立受体针对供体抗原特异性T淋巴细胞克隆，转入自杀基因诱导移植耐受的可行性。
Objective to explore the feasibility that the recipient against donor antigen specific t lymphocytes clones are formed, and the suicide genes are induced into the clone.
于耐受诱导后30 d对受体小鼠作耐受状态的检查，包括供体特异性皮肤移植、混合淋巴细胞反应(MLR)及迟发型超敏反应(DTH)。
Recipient B6 mice were characterized for the tolerance status with donor Lewis rat skin graft, mixed lymphocyte reaction (MLR), and delayed - type hypersensitivity (DTH) assays after 30 days.
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