DNA二级结构—双螺旋结构 苷酸(以G表示)和胞嘧啶核苷酸(以C表示)的含量相等,双链间的碱基以互补形式存在,即A-T和G-C,这种对应的两个碱基称为碱基对(base pair,bp),彼此以氢键相连。在A-T之间有两个氢键,在G-C之间有三个氢键,因而G-C间的结合力大于A-T间的
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目前为止的示例都假定 DNA 碱基对之间不匹配的扣分应该相等 —例如,认为 G 变异为 A 与变异为 C 的可能性相当。
The examples so far have naively assumed that the penalty for a mismatch between DNA bases should be equal — for example, that a G is as likely to mutate into an A as a C.
目前为止的示例都假定DNA碱基对之间不匹配的扣分应该相等-例如,认为G变异为A与变异为C的可能性相当。
The examples so far have naively assumed that the penalty for a mismatch between DNA bases should be equal - for example, that a G is as likely to mutate into an a as a c.
所用的菌种为TA98和TA10 0 ,主要考察碱基对置换突变和移码致突变。
In Ames assay the strains were TA98 and TA100, which were able to determine base pair substitutions and frameshift mutation respectively.
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