结果:与NS1骨髓瘤细胞同一孔池中培养的DC的数目减少,形态改变,抗原递呈功能下降。
Results: the number of DC which were cultured in the same Wells with NS1 tend to decrease, the cellular appearance changed and the ability of presenting antigen decreased.
第一信号为抗原与T细胞受体TCR的结合,第二信号为抗原递呈细胞上的协同刺激分子与T、B淋巴细胞上的受体结合。
The first signal is the binding of antigen with TCR on T cells. The second signal is the binding of co-stimulate on the APC with their receptors presenting on T and B lymphocytes.
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