It is generally agreed that artemisinins action mechanism is associated with the endoperoxide function, but some researchers have some other ideas.
一般认为,青蒿素类药物的作用机制与其结构中的内过氧桥有关,最近又提出一些与以往不同的观点。
These results suggest that MK-447 may selectively enhance the prostaglandin I2 (PGI2) level by acting as a tryptophan-like cofactor of PG endoperoxide synthetase.
研究结果提示,MK-447很可能是通过作为前列腺素酯氧酶色氨酸样协同因子,从而发挥选择性增加PGI_2生成的作用。
The conversion rate from AA into PGG2 and PGH2 by chemical reaction and column chromatography was about 34%. The purity of endoperoxide products was more than 90%.
通过化学反应和柱层析,AA转变为PGG_2和PGH_2的转换率大约为34%,前列腺素内过氧化物的纯度可达90%以上。
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