Henson, who won the last of his 31 Wales caps against Ireland in March 2009, wants to be considered for Welsh selection in a competitive-looking midfield that includes Jamie Roberts, Jonathan Davies and James Hook plus experienced injured duo Andrew Bishop and Tom Shanklin.
Five more players - Wales duo Mike Phillips and Alun-Wyn Jones, Ireland flanker Stephen Ferris plus England pair Riki Flutey and Lee Mears - could also taste their first action as a Lion off the bench.