量效关系(dose-effect relationship):在一定剂量范围内,药物剂量的大小与血药浓度高低成正比,亦与药效的强弱有关,这种剂量与效应的关系称为量效关系。
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(二)剂量效应关系和剂量反应关系剂量-效应关系(dose-effect relationship)或剂量-反应关系(dose-response relationship)是毒理学的重要概念,即随着外源化学物的剂量增加,对机体的毒效应的程度增加,或出现...
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... 最大无作用剂量(maximal no-effect level,MNEL) 剂量效应关系(dose-effect relationship) 剂量反应关系(dose-response relationship) ...
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quantitative dose-effect relationship 量反应型量效关系
linear dose-effect relationship 线性的剂量效应关系
time dose-effect relationship 时反应型量效关系
drug dose effect relationship 药物剂量效应关系
had dose-effect relationship 呈量效关系
show a dose-effect relationship 呈量效关系
shows a dose-effect relationship 呈量效关系
The experiment proved to significantly reduce blood pressure at spontaneously hypertensive rats (SHR) blood pressure, with the dose-effect relationship.
结果:1)降压一号可以明显降低自发性高血压大鼠血压,且具有量效关系。
参考来源 - 降压一号对自发性高血压大鼠脑皮质组织的保护The result indicated that the level of DNA damage reached the peak at 2 h after a single oral administration of toxin,and at this time the dose-effect relationship was obviously.
试验表明,一次经口染毒AFB_1 2h后雏鸭肝细胞DNA损伤达到高峰,此时DNA损伤程度与AFB_1暴露之间的量效关系最为明显。
参考来源 - 黄曲霉毒素B·2,447,543篇论文数据,部分数据来源于NoteExpress
The distance of DNA migration in BALF and PBMC increased with a dose-effect relationship.
各剂量组PBMC、BALF细胞的DNA迁移长度显著增加,有剂量效应关系。
The influence of Xinmailong(XML) on the blood pressure and its dose-effect relationship were studies on anaesthetized cats.
本文主要研究心脉龙注射液对正常猫血压的影响及其量效关系。
MATDA can damage DNA and induce unscheduled DNA synthesis (UDS) in human lymphocytes in vitro, on a dose-effect relationship.
敌枯双在体外对人淋巴细胞的UDS(程序外d NA合成)有诱导作用,呈剂量-反应关系。
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