In addition to the familiar duplex DNA, certain G-rich DNA sequences can fold into a variety of four-stranded structures, which are called G-quadruplexes.
富含鸟嘌呤碱基的DNA序列能够通过鸟嘌呤环的互联作用形成四链螺旋结构，这种结构被称为G-四链体。
It revealed that imide derivative 4, a potent binder of HIV-1 DNA, had the higher binding affinity with the duplex DNA among six DNA-recognizing mole-cules.
在研究中比较了不同识别分子与靶序列DNA结合的强弱，发现双萘酰亚胺衍生物4对此序列DNA具有高亲合性的结合，并分析了识别分子与DNA复合物的碎裂机理以及结合模式。
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