Age at onset: birth; symptoms include general muscle weakness and possible joint deformities; disease progresses slowly; shortened life span. [ citation needed ]
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The disease progresses slowly so that most are totally blind by the time they're in their 30s or early 40s.
这种疾病发展缓慢,多数人到三十多岁或四十出头就完全失明。
The nearly 2,300 patients in the trial all had a relatively stable form of coronary artery disease that generally progresses slowly.
研究中入组的2300例患者均存在进展缓慢且比较稳定的冠脉病变。
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