Despite your best efforts, the first two steps might not work.

尽管你做了最大的努力，前两步可能不起作用。

youdao

Sometimes, despite your best efforts otherwise, life will give you lemons.

有时候，尽管你付出了最大的努力，人生却不如意。

youdao

Despite your best efforts, passion, habits and a flow-producing environment can fail.

尽管你尽了最大的努力，激情、习惯和激发意志的环境也可能没有效果。

youdao

Mr. GAFFNEY: Two technical provisions that are (cross talk) despite your best efforts.

CENTERFORSECURITYPOLICY: Transcript of CNBC Divest Terror debate

Sadly, despite your best efforts, most likely you will fail.

FORBES: The Innovator��s Paradox

The best thing to do is to prepare for them before they arise and then talk about them when they come up despite your best efforts to avoid them.

FORBES: When One Partner Leans In, What Happens To The Rest?