The preparation method of Chinese medicine composition for curing AIDS with obvious therapeutic effect includes the following steps: decocting 9 Chinese medicinal materials of astragalus root, caragana arborescens, tangerine peel, maoshan atractylodes root, fenxinmu, jujube, red ganoderma, ginseng and rock candy at twice, filtering, combining filtrates, adding fine poria powder, cordyceps powder and stir-fried ovate atractylodes root powder, low-temp. reduced pressure distillation and concentration, spray-drying concentrate to obtain the medicinal powder.

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