Accounting for heterogeneous differentiaton status and proliferation potential, cancer stem cells and non-tumorigenic cancer cells may vary in clonogenicity ability in vitro, as well as the phenotypes of their colonies.
由于肿瘤干细胞与非成瘤性肿瘤细胞在分化程度、增殖能力上存在差异,所以体外培养时两者的克隆形成能力可能也会不同,并可能形成不同表型的克隆。
参考来源 - 基于克隆异质性筛选和鉴定人胶质瘤干细胞及其机制的初步研究·2,447,543篇论文数据，部分数据来源于NoteExpress
MethodsA clone formation assay was carried out to determine the clonogenicity and regeneration ability of cells.
方法采用有限稀释法，检测细胞单克隆形成的数量及大小；
Hair follicle stem cells are considered to be slow cycling cells endowed with a superior proliferative capacity and clonogenicity.
毛囊干细胞定位在毛囊突出区，具有所有成体干细胞的共性—慢周期、未分化、自我更新能力及体外增殖能力强等。
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