Aim To induce cisplatin-resistant esophageal squamous carcinoma cell line and investigate the mechanisms by which the cancer cells develop drug resistance.
目的诱导对顺铂耐药的人食管鳞癌细胞株,并进一步研究细胞耐药性产生的机制。
参考来源 - 顺铂降低铜离子转运蛋白1表达诱导人食管鳞癌细胞耐药·2,447,543篇论文数据，部分数据来源于NoteExpress
Objective: To establish a cisplatin-resistant ovarian cancer cell line COC1/DDP, and investigate the mechanism of resistance.
目的：建立人卵巢癌顺铂耐药细胞株COC1/DDP，探讨其耐药的机制。
ConclusionThere exists internal relations between the chemoresistance and radiosensitivity of lung adenocarcinoma cisplatin-resistant cell, chemo-resistance leads to reduced radiosensitivity.
结论肺腺癌细胞的化疗耐药性与放射敏感性之间有一定的内在联系，化疗耐药性导致放疗敏感性降低。
When PIDD levels are artificially increased in human lung cancer cells, they become more resistant to cisplatin.
当PIDD水平在肺癌细胞人为增加时，它们对顺铂耐药性增强。
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