Objective Multidrug resistance can eventually result in the chemotherapy failure of acute leukemia.

目的多药耐药性是导致急性白血病化疗失败的主要原因。

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Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure.

临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药（MDR）。

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BACKGROUND & OBJECTIVE: Multidrug resistance plays an important role in chemotherapy failure of bladder cancer, but its mechanism is unclear.

背景与目的：多药耐药在膀胱癌化疗失败中起着重要作用，关于其机制还不是十分清楚。

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Doctors prescribe it for the anemia that occurs with kidney failure and chemotherapy.

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The data show that, after failure of second-line chemotherapy, lung-cancer patients rarely get any added survival time from further treatments and often suffer significant side effects.

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The study, of patients with non-small cell lung cancer who were also receiving chemotherapy, showed an increase in "local failure, " meaning cancer cells at the radiation site either weren't killed or began growing.

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