The results indicate that ACN could induce changes in the levels of ABP and inhibin gene expression in testes of male SD rats, that may damage Sertoli cells in testes.

ACN对大鼠睾丸中ABP和抑制素基因表达水平有影响，提示丙烯腈对睾丸中支持细胞可能有损伤作用。

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Objective: to construct cell model of spermatogonial stem cells (SSCs) with Sertoli cell layer in vitro, and study the proliferation characteristic of SSCs in vitro.

目的：建立体外研究精原干细胞与支持细胞共培养的细胞模型，探讨体外精原干细胞在支持细胞层上的增殖特点。

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The result: we got plenty of sertoli cells which were high purity (78.3%) and high viability (90.7%).

最终获得了大量较高纯度(78.3%)和高活率(90.7%)的支持细胞。

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