Conclusion The polymorphisms of XRCC1 A194W and A399Q contribute to susceptibility to lead poisoning, which may be suggested as important biomarkers of susceptibility to lead poisoning.
结论XRCC1 A194W和A399 Q基因多态性与铅中毒易感性有关，可考虑作为铅中毒的重要易感性生物学标志。
There is also a need to identify prognostic markers of disease susceptibility, biomarkers of disease progression and improved technologies to monitor the effectiveness of new therapies.
还有一个需要，以确定疾病的易感性的预后指标，生物标志物来监测疾病的进展和改进的技术新疗法的有效性。
We reviewed the advances of molecular cancer eipdemiology and biomarkers of cancer susceptibility gene. The chances and challenge of molecular cancer eipdemiology research were also discussed.
综述了肿瘤分子流行病学和肿瘤易感基因生物学标志的研究现状，并展望了肿瘤分子流行病学研究的机遇和挑战。
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