So this work is a big leap forward in our understanding of the origins of the disease.

所以这项工作对于我们理解这种疾病的来源是一个巨大的跨越。

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You'll have the confidence to take that big leap forward if you're feeling grounded, centered and organized.

如果你们正感觉到被支持，有中心的并有组织的，你们将拥有信心向前迈出那一步重大的飞跃。

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When Apple took the wraps off Mac OS X a decade ago, it clearly marked a big leap forward from the old Mac operating system.

苹果公司10年前发布的Mac OS X显然标志着旧的Mac操作系统的一大迈步。

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What that means is that we identify students who are going to take a big leap, intellectual leap forward in this coming year, a spurt forward in this coming year.

测试能让我们找出,将在新学年在学业上，取得巨大进步的学生，在新学年取得巨大进步。

哈佛公开课 - 幸福课课程节选

The really big leap forward will come with third-generation handsets.

ECONOMIST: A splash of mobile colour | The

Mobile gaming on the iPhone or iPod touch takes a big leap forward with the iFrogz Caliber Advantage, a tactile, analog game controller that directly attaches to the mobile device.

ENGADGET: iFrogz's Caliber Advantage iPhone 5 gaming case hands-on

Delivering a resolution of eight million pixels, four times the resolution of HDTV, Ultra HD (4K) is poised to mark the next big leap forward in the immersive viewing experience.

ENGADGET: First Ultra HD channel goes live in Europe HD