Spanish No.6 David Ferrer looked comfortable as he beat France's Benoit Paire 6-3 6-3 6-2.

CNN: Nadal cruises as Murray battles back at French Open

Nishikori, meanwhile, became the first Japanese man in 75 years to reach the French Open's fourth round, beating Frenchman Benoit Paire.

NPR: Djokovic's Day At The French Open Ends In Despair

"It was not very comfortable and it affected my game, " Nadal told reporters ahead of his third-round tie with Frenchman Benoit Paire.

CNN: Nadal shrugs off Monaco hangover with Barcelona win