Catch the mouse problem. If you have to reach for it, then your seated posture may be out of whack.

鼠标的问题。 如果你要伸手够才能拿到鼠标，你的坐姿肯定有问题。

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The ecosystem will be thrown out of whack.

生态系统将出现问题。

《柯林斯英汉双解大词典》

Your center of gravity has shifted and all that extra weight around your middle may be pulling your back out of whack and messing with your balance.

你的重心已经发生偏移了，所有环绕在你腰腹部的增加的重量可能会使背部不一致并干扰你的平衡力。

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The study points to human activity as the cause, because of the suddenness of the shift in temperature which appears to be out of whack with long-term trends.

WSJ: Earth Hotter Now Than Most of Past 11,000 Years

Nothing could be more completely out of whack with what is important to the American people and to getting our economy going again than to watch a debate about billionaire tax cuts while people lose their unemployment benefits.

WHITEHOUSE: Press Briefing

With used-car values already out of whack, shoppers need to be extra cautious to avoid compounding an already unfavorable financial situation by selecting a more problematic model that will require costly out-of-warranty repair work.

MSN: Used-car clunkers to avoid